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Fish and Amphibian Embryos as Alternative Models in Toxicology and Teratology

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[warning]11th-12th October 2012
Paris, France


Fish and amphibian embryo models are gaining increasing popularity in the area of toxicology, both in research and potential regulatory application. These models exhibit a number of advantages which make them superior and/or complementary to others. In compliance with international animal welfare regulations, the fish and amphibian embryo models provide an ethically acceptable small scale analysis system with the complexity of a complete organism. A suite of available advanced methodologies allows various types of experimental approaches ranging from phenotypic observations to “omics” analysis. The ultimate goal of the symposium is to promote the development of the fish and frog embryo models as potential alternatives to animal testing.

A first very succesful workshop was hold in 2010 in Karlsruhe, Germany with a strong focus on the zebrafish model. While the zebrafish remains one of the most important model the second symposium and workshop will extend its focus to other fish and amphibian species with similar features. The symposium aims to bring together scientists using fish and frog embryo models, exchange knowledge, ideas and latest developments in the context of toxicology and teratology. Invited lectures will focus on specific topics. Discussion groups will allow to identify major advantages, limitations, new fields and future research needs of the fish/amphibian embryo model and to establish collaborations.

Contributions welcome

Contributions from participants, both poster presentations and a limited number of short platform presentations are welcome. These presentations could cover one of the following topics: human toxicology screening, teratogenicity, nanotoxicology, immunotoxicity, regulatory toxicology, endocrine effects, neurotoxicity, toxicogenomics (‘omics‘), high throughput technologies, functional genomics, ethics/animal welfare and ecotoxicology (acute and chronic toxicity, bioconcentrations effluent testing).

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